Jump to main content
Jump to site search

Issue 38, 2013
Previous Article Next Article

Shape memory poly(ε-caprolactone)-co-poly(ethylene glycol) foams with body temperature triggering and two-way actuation

Author affiliations

Abstract

We describe the fabrication of porous foams with shape memory triggering at body temperature. Employing a modified porogen-leaching technique, functionalized poly(ε-caprolactone) (PCL) and poly(ethylene glycol) (PEG) macromers are crosslinked via thiol–ene chemistry to generate highly porous foam scaffolds with shape memory capacity. The temperature at which shape change of these scaffolds occurs under hydrated conditions can be tuned both through control of the chemical composition and through deformation temperature during mechanical programming of the scaffolds. Uniquely, the foams exhibit reversible actuation in compression, which has not previously been demonstrated for foams. Our results indicate that PCL–PEG shape memory foams have potential as programmable scaffolds for tissue engineering, regenerative medicine, and the study of cell mechanobiology.

Graphical abstract: Shape memory poly(ε-caprolactone)-co-poly(ethylene glycol) foams with body temperature triggering and two-way actuation

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Jun 2013, accepted on 19 Aug 2013 and first published on 19 Aug 2013


Article type: Communication
DOI: 10.1039/C3TB20810A
Citation: J. Mater. Chem. B, 2013,1, 4916-4920
  •   Request permissions

    Shape memory poly(ε-caprolactone)-co-poly(ethylene glycol) foams with body temperature triggering and two-way actuation

    R. M. Baker, J. H. Henderson and P. T. Mather, J. Mater. Chem. B, 2013, 1, 4916
    DOI: 10.1039/C3TB20810A

Search articles by author

Spotlight

Advertisements