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Issue 45, 2013
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First bisphosphonate hydrogelators: potential composers of biocompatible gels

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Abstract

Recently, investigation of hydrogels has gained ever increasing attention mostly because of their biomedical and pharmaceutical properties, and novel hydrogelators are constantly studied to find functional applications. Bisphosphonates (BPs) are well-known compounds applicable in different fields but are mostly used in clinics as drugs for bone-related diseases. In this study, a novel class of BP-hydrogelators together with a BP-organogelator was found, and the gelating abilities of the compounds were studied. Several techniques to analyze the structure and the properties of the formed gels were used, including solid state 13C and 31P CPMAS and solution state NMR spectroscopy, IR spectroscopy, PXRD, thermoanalysis, as well as SEM.

Graphical abstract: First bisphosphonate hydrogelators: potential composers of biocompatible gels

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Publication details

The article was received on 09 Jul 2013, accepted on 22 Sep 2013 and first published on 24 Sep 2013


Article type: Paper
DOI: 10.1039/C3TB20957A
Citation: J. Mater. Chem. B, 2013,1, 6201-6212
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    First bisphosphonate hydrogelators: potential composers of biocompatible gels

    A. Alanne, M. Lahtinen, M. Löfman, P. Turhanen, E. Kolehmainen, J. Vepsäläinen and E. Sievänen, J. Mater. Chem. B, 2013, 1, 6201
    DOI: 10.1039/C3TB20957A

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