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Issue 27, 2013
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Dissipative interactions in cell–matrix adhesion

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The mechanical properties of cell microenvironments, cells themselves and the linking biomolecular constituents are increasingly recognized as important parameters in understanding and controlling cell behaviour. Specifically, cell adhesion – the first step of interaction – controls many processes in cell signalling. In this context the viscoelastic characteristics of involved biopolymer systems have to be considered as a key to the understanding of the underlying mechanisms. While elasticity is currently heavily addressed in biophysical and biomaterials science, studies on viscous and dissipative contributions are underrepresented and their impact is frequently neglected. In this review we point out that there is a need to overcome this imbalance and to reveal the impact of dissipative processes in cell–matrix interaction.

Graphical abstract: Dissipative interactions in cell–matrix adhesion

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Publication details

The article was received on 20 Mar 2013, accepted on 09 May 2013, published on 04 Jun 2013 and first published online on 04 Jun 2013

Article type: Review Article
DOI: 10.1039/C3SM50803J
Citation: Soft Matter, 2013,9, 6207-6216
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    Dissipative interactions in cell–matrix adhesion

    C. Müller, A. Müller and T. Pompe, Soft Matter, 2013, 9, 6207
    DOI: 10.1039/C3SM50803J

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