Jump to main content
Jump to site search

Issue 11, 2013
Previous Article Next Article

Interactions between cells or proteins and surfaces exhibiting extreme wettabilities

Author affiliations

Abstract

Regulation of protein adsorption and cell adhesion on surfaces is a key aspect in the field of biomedicine and tissue engineering. Beside the general studies on hydrophilic/hydrophobic surfaces, there are both fundamental and practical interests to extend the investigation of the interaction between proteins or cells and surfaces to the two extreme wettability ranges, namely superhydrophilicity and superhydrophobicity. This review gave an overview of recent studies on proteins or cells action on these two special wettability ranges. The first part will focus on the interaction between proteins and superhydrophilic/superhydrophobic surfaces. The second part will focus on cells adhesion on these extreme wettable surfaces. Surfaces can be patterned to control in space the wettability within extreme values. As an application of such substrates, flat chips for high-throughput screening are also addressed to offer new insight on the design of a new type of bioanalysis supports.

Graphical abstract: Interactions between cells or proteins and surfaces exhibiting extreme wettabilities

Back to tab navigation

Publication details

The article was received on 28 Nov 2012, accepted on 07 Jan 2013 and first published on 12 Feb 2013


Article type: Review Article
DOI: 10.1039/C3SM27739A
Citation: Soft Matter, 2013,9, 2985-2999
  •   Request permissions

    Interactions between cells or proteins and surfaces exhibiting extreme wettabilities

    W. Song and J. F. Mano, Soft Matter, 2013, 9, 2985
    DOI: 10.1039/C3SM27739A

Search articles by author

Spotlight

Advertisements