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Issue 33, 2013
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Complex dynamics of a bilamellar vesicle as a simple model for leukocytes

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Abstract

The influence of the internal structure of a biological cell (e.g., a leukocyte) on its dynamics and rheology is not yet fully understood. By using 2D numerical simulations of a bilamellar vesicle (BLV) consisting of two vesicles as a cell model, we find that increasing the size of the inner vesicle (mimicking the nucleus) triggers a tank-treading-to-tumbling transition. A new dynamical state is observed, the undulating motion: the BLV inclination with respect to the imposed flow oscillates while the outer vesicle develops rotating lobes. The BLV exhibits a non-Newtonian behavior with a time-dependent apparent viscosity during its unsteady motion. Depending on its inclination and on its inner vesicle dynamical state, the BLV behaves like a solid or a liquid.

Graphical abstract: Complex dynamics of a bilamellar vesicle as a simple model for leukocytes

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Publication details

The article was received on 15 Apr 2013, accepted on 05 Jun 2013 and first published on 05 Jun 2013


Article type: Paper
DOI: 10.1039/C3SM51032H
Citation: Soft Matter, 2013,9, 8057-8061
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    Complex dynamics of a bilamellar vesicle as a simple model for leukocytes

    B. Kaoui, T. Krüger and J. Harting, Soft Matter, 2013, 9, 8057
    DOI: 10.1039/C3SM51032H

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