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Issue 1, 2013
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Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

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Abstract

We review recent advances in multiscale modeling of the mechanics of healthy and diseased red blood cells (RBCs), and blood flow in the microcirculation. We cover the traditional continuum-based methods but also particle-based methods used to model both the RBCs and the blood plasma. We highlight examples of successful simulations of blood flow including malaria and sickle cell anemia.

Graphical abstract: Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

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Publication details

The article was received on 14 Aug 2012, accepted on 04 Oct 2012 and first published on 22 Oct 2012


Article type: Tutorial Review
DOI: 10.1039/C2SM26891D
Citation: Soft Matter, 2013,9, 28-37
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    Continuum- and particle-based modeling of shapes and dynamics of red blood cells in health and disease

    X. Li, P. M. Vlahovska and G. E. Karniadakis, Soft Matter, 2013, 9, 28
    DOI: 10.1039/C2SM26891D

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