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Issue 36, 2013
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CMAS: fully integrated portable centrifugal microfluidic analysis system for on-site colorimetric analysis

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Abstract

A portable, wireless system capable of in situ reagent-based colorimetric analysis is demonstrated. The system is based on a reconfigurable low cost optical detection method employing a paired emitter detector diode device, which allows a wide range of centrifugal microfluidic layouts to be implemented. Due to the wireless communication, acquisition parameters can be controlled remotely and results can be downloaded in distant locations and displayed in real time. The stand-alone capabilities of the system, combined with the portability and wireless communication, provide the flexibility crucial for on-site water monitoring. The centrifugal microfluidic disc presented here is designed for nitrite detection in water samples, as a proof of principle. A limit of detection of 9.31 ppb, along with similar coefficients of correlation and precision, were obtained from the Centrifugal Microfluidic Analysis System compared with the same parameters measured using a UV-Vis spectrophotometer.

Graphical abstract: CMAS: fully integrated portable centrifugal microfluidic analysis system for on-site colorimetric analysis

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Publication details

The article was received on 14 Jun 2013, accepted on 04 Jul 2013 and first published on 05 Jul 2013


Article type: Paper
DOI: 10.1039/C3RA42975J
Citation: RSC Adv., 2013,3, 15928-15938
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    CMAS: fully integrated portable centrifugal microfluidic analysis system for on-site colorimetric analysis

    M. Czugala, D. Maher, F. Collins, R. Burger, F. Hopfgartner, Y. Yang, J. Zhaou, J. Ducrée, A. Smeaton, K. J. Fraser, F. Benito-Lopez and D. Diamond, RSC Adv., 2013, 3, 15928
    DOI: 10.1039/C3RA42975J

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