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Issue 39, 2013
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Facile synthesis and newly found biological activity of aminolyzed tung oil components with conjugated double bonds

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Abstract

Three novel hydroxylated tung oil (HTO) components with three conjugated double bonds were synthesized by aminolysis of tung oil with diethylolamine, and their cytotoxic effects on five human tumor cell lines were revealed for the first time. Compared with conjugated linolenic acid (CLnA) and conjugated linoleic acid (CLA) which have anti-cancer activity, the carboxyl-free HTO compounds also exhibited a cytotoxic effect against some tumor cell lines.

Graphical abstract: Facile synthesis and newly found biological activity of aminolyzed tung oil components with conjugated double bonds

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Publication details

The article was received on 08 Jun 2013, accepted on 25 Jul 2013 and first published on 31 Jul 2013


Article type: Communication
DOI: 10.1039/C3RA42860E
Citation: RSC Adv., 2013,3, 17712-17716
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    Facile synthesis and newly found biological activity of aminolyzed tung oil components with conjugated double bonds

    Z. Ren, C. Zhang, L. Jiang, H. Wang, W. Zhao, Y. Fu and Y. Zhang, RSC Adv., 2013, 3, 17712
    DOI: 10.1039/C3RA42860E

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