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Issue 38, 2013
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Organocatalyzed aza-Michael–Michael cascade reactions to construct spirooxindole tetrahydroquinolines with all-carbon chiral centers

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Abstract

An efficient organocatalytic aza-Michael–Michael cascade reaction for the asymmetric synthesis of highly functionalized spirooxindole tetrahydroquinolines has been reported through a formal [4+2] annulation strategy.

Graphical abstract: Organocatalyzed aza-Michael–Michael cascade reactions to construct spirooxindole tetrahydroquinolines with all-carbon chiral centers

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Publication details

The article was received on 05 Jun 2013, accepted on 25 Jul 2013 and first published on 26 Jul 2013


Article type: Communication
DOI: 10.1039/C3RA42783H
Citation: RSC Adv., 2013,3, 16999-17002
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    Organocatalyzed aza-Michael–Michael cascade reactions to construct spirooxindole tetrahydroquinolines with all-carbon chiral centers

    Y. Huang, C. Zheng and G. Zhao, RSC Adv., 2013, 3, 16999
    DOI: 10.1039/C3RA42783H

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