Issue 38, 2013

Organocatalyzed aza-Michael–Michael cascade reactions to construct spirooxindole tetrahydroquinolines with all-carbon chiral centers

Abstract

An efficient organocatalytic aza-Michael–Michael cascade reaction for the asymmetric synthesis of highly functionalized spirooxindole tetrahydroquinolines has been reported through a formal [4+2] annulation strategy.

Graphical abstract: Organocatalyzed aza-Michael–Michael cascade reactions to construct spirooxindole tetrahydroquinolines with all-carbon chiral centers

Supplementary files

Article information

Article type
Communication
Submitted
05 Jun 2013
Accepted
25 Jul 2013
First published
26 Jul 2013

RSC Adv., 2013,3, 16999-17002

Organocatalyzed aza-Michael–Michael cascade reactions to construct spirooxindole tetrahydroquinolines with all-carbon chiral centers

Y. Huang, C. Zheng and G. Zhao, RSC Adv., 2013, 3, 16999 DOI: 10.1039/C3RA42783H

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