Issue 32, 2013
From the journal:

RSC Advances

Stereoselective synthesis of short benzylmalonyl peptides†

Emanuele Aresu,a   Stefania Fioravanti,*a   Simona Gasbarri,a   Lucio Pellacania  and  Fabio Sciubbaa  

* Corresponding authors

a Dipartimento di Chimica, Università degli Studi di Roma “La Sapienza”, P.le Aldo Moro 5, I-00185 Roma, Italy
E-mail: stefania.fioravanti@uniroma1.it
Fax: +39 06490631
Tel: +39 0649913098

Abstract

A Rh-catalyzed addition reaction on non symmetric dehydro alanine retro-peptides is the key step in the reported three-step strategy for the diastereoselective synthesis of differently functionalized benzyl malonyl peptides (74% overall yield).

Graphical abstract: Stereoselective synthesis of short benzyl malonyl peptides

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Article information

DOI
https://doi.org/10.1039/C3RA41852A
Article type
Paper
Submitted
17 Apr 2013
Accepted
31 May 2013
First published
03 Jun 2013

RSC Adv., 2013,3, 13470-13476

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Stereoselective synthesis of short benzyl malonyl peptides

E. Aresu, S. Fioravanti, S. Gasbarri, L. Pellacani and F. Sciubba, RSC Adv., 2013, 3, 13470 DOI: 10.1039/C3RA41852A

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