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Issue 7, 2013
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Hyperbranched polymers for bioimaging

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Hyperbranched polymers (HBPs) are highly branched macromolecules with a three-dimensional dendritic architecture. Benefiting from their highly branched topological structures, convenient synthetic procedures and unique physical/chemical properties, HBPs have been used to construct bioimaging probes and contrast agents, which exhibit enhanced stability, reduced toxicity, prolonged plasma half-life, and improved targeting specificity. Recently, the combination of these HBP-based probes or contrast agents with various imaging modalities showed great potential in biological imaging, including optical imaging, magnetic resonance imaging, nuclear imaging, and ultrasound imaging. This review summarizes the current advances in HBPs for bioimaging as well as their potential applications in clinical diagnosis.

Graphical abstract: Hyperbranched polymers for bioimaging

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Publication details

The article was received on 18 Sep 2012, accepted on 04 Nov 2012 and first published on 06 Nov 2012

Article type: Review Article
DOI: 10.1039/C2RA22210H
Citation: RSC Adv., 2013,3, 2071-2083
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    Hyperbranched polymers for bioimaging

    Q. Zhu, F. Qiu, B. Zhu and X. Zhu, RSC Adv., 2013, 3, 2071
    DOI: 10.1039/C2RA22210H

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