Single molecular hyperbranched nanoprobes for fluorescence and magnetic resonance dual modal imaging†
Abstract
We designed and synthesized a gadolinium(III)-decorated hyperbranched polyglycerol with a fluorescent polyhedral oligomeric silsesquioxane core (POSS–HPG–Gd), and demonstrated its application as a single-molecular nanoprobe for fluorescence and magnetic resonance dual imaging. The nanoprobe exhibited a uniform size with a mean diameter of 6 ± 1 nm revealed by