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Issue 45, 2013
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Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones

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Abstract

Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones are reported. The spiro[pyrazolin-3,3′-oxindole] products are formed in good yields (up to 98%) and high enantioselectivity (up to 99% ee).

Graphical abstract: Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones

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Publication details

The article was received on 06 Sep 2013, accepted on 05 Oct 2013 and first published on 09 Oct 2013


Article type: Communication
DOI: 10.1039/C3OB41815D
Citation: Org. Biomol. Chem., 2013,11, 7834-7837
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    Catalytic, enantioselective 1,3-dipolar cycloadditions of nitrile imines with methyleneindolinones

    A. L. Gerten, M. C. Slade, K. M. Pugh and L. M. Stanley, Org. Biomol. Chem., 2013, 11, 7834
    DOI: 10.1039/C3OB41815D

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