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Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma

Kai Liu,a   Datong Zhang,b   Jeremy Chojnacki,a   Yuhong Du,c   Haian Fu,c   Steven Grantd and   Shijun Zhang*a  
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Department of Medicinal Chemistry, Virginia Commonwealth University, Richmond, USA
School of Chemistry and Pharmaceutical Engineering, Shandong Polytechnic University, Jinan, P.R. China
Department of Pharmacology and Emory Chemical Biology Discovery Center, Emory University, Atlanta, USA
Department of Internal Medicine and Massey Cancer Center, Virginia Commonwealth University, Richmond, USA
Org. Biomol. Chem., 2013,11, 4757-4763

DOI: 10.1039/C3OB40595H
Received 25 Mar 2013, Accepted 07 Jun 2013
First published online 11 Jun 2013
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