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Issue 18, 2013
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An expedient stereoselective and chemoselective synthesis of bicyclic oxazolidinones from quinols and isocyanates

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Abstract

A mild and efficient synthesis of bicyclic oxazolidinones from quinols and isocyanates, under DBU-mediated conditions at room temperature, is described. The aza-Michael addition to substituted cyclohexadienones is stereoselective and chemoselective.

Graphical abstract: An expedient stereoselective and chemoselective synthesis of bicyclic oxazolidinones from quinols and isocyanates

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Publication details

The article was received on 09 Jan 2013, accepted on 09 Mar 2013 and first published on 12 Mar 2013


Article type: Communication
DOI: 10.1039/C3OB00047H
Citation: Org. Biomol. Chem., 2013,11, 2939-2942
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    An expedient stereoselective and chemoselective synthesis of bicyclic oxazolidinones from quinols and isocyanates

    J. Zhang, J. Wu, Z. Yin, H. Zeng, K. Khanna, C. Hu and S. Zheng, Org. Biomol. Chem., 2013, 11, 2939
    DOI: 10.1039/C3OB00047H

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