Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Tuesday 19th September 2017 from 8.00am to 4.00pm (BST).

During this time our website performance may be temporarily affected. If you have any questions please use the feedback button available under our menu button. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 42, 2013
Previous Article Next Article

Dual-sugar imaging using isonitrile and azido-based click chemistries

Author affiliations

Abstract

We report the first account of metabolically labelling N-acetylglucosamine, in conjunction with either N-acetylgalactosamine or N-acetylmannosamine using a combination of isonitrile- and azide-based chemistries. With the appropriately labelled fluorescent probe molecules, that react with either the azido or isonitrile groups, the method enabled co-visualisation of cancer cell glycoproteins.

Graphical abstract: Dual-sugar imaging using isonitrile and azido-based click chemistries

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Jul 2013, accepted on 13 Sep 2013 and first published on 16 Sep 2013


Article type: Paper
DOI: 10.1039/C3OB41805G
Citation: Org. Biomol. Chem., 2013,11, 7297-7300
  •   Request permissions

    Dual-sugar imaging using isonitrile and azido-based click chemistries

    Y. A. Wainman, A. A. Neves, S. Stairs, H. Stöckmann, H. Ireland-Zecchini, K. M. Brindle and F. J. Leeper, Org. Biomol. Chem., 2013, 11, 7297
    DOI: 10.1039/C3OB41805G

Search articles by author

Spotlight

Advertisements