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Asymmetric Mannich reactions of imidazo[2,1-b]thiazole-derived nucleophiles with (SS)-N-tert-butanesulfinyl (3,3,3)-trifluoroacetaldimine

Haibo Mei,ab   Chen Xie,a   Lingmin Wu,a   Vadim A. Soloshonok,cd   Jianlin Han*ab and   Yi Pan*ae  
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a
School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, China
E-mail: hanjl@nju.edu.cn;
Fax: +86-25-83593153 ;
Tel: +86-25-83593153
b
Institute for Chemistry & BioMedical Sciences, Nanjing University, Nanjing, 210093, China
c
Department of Organic Chemistry I, Faculty of Chemistry, University of the Basque Country UPV/EHU, 20018 San Sebastian, Spain
d
IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain
e
State Key Laboratory of Coordination, Nanjing University, Nanjing, 210093, China
E-mail: yipan@nju.edu.cn
Org. Biomol. Chem., 2013,11, 8018-8021

DOI: 10.1039/C3OB41785A
Received 02 Sep 2013, Accepted 17 Oct 2013
First published online 17 Oct 2013
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