Issue 38, 2013
From the journal:

Organic & Biomolecular Chemistry

N-Heterocyclic carbene catalyzed regioselective oxo-acyloxylation of alkenes with aromatic aldehydes: a high yield synthesis of α-acyloxy ketones and esters†

Rambabu N. Reddi,a   Pushpa V. Malekara  and  Arumugam Sudalai*a  

* Corresponding authors

a Chemical Engineering and Process Development Division, National Chemical Laboratory (CSIR), Pashan Road, Pune, India
E-mail: a.sudalai@ncl.res.in
Fax: +91-02025902675

Abstract

An N-heterocyclic carbene (NHC)-catalyzed reaction of alkenes with aromatic aldehydes providing for a high yield synthesis of α-acyloxy ketones and esters has been described. This unprecedented regioselective oxidative process employs NBS and Et3N in stoichiometric amounts and O2 (1 atm) as an oxidant under ambient conditions in DMSO as a solvent.

Graphical abstract: N-Heterocyclic carbene catalyzed regioselective oxo-acyloxylation of alkenes with aromatic aldehydes: a high yield synthesis of α-acyloxy ketones and esters

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3OB41551A
Article type
Communication
Submitted
29 Jul 2013
Accepted
05 Aug 2013
First published
07 Aug 2013

Org. Biomol. Chem., 2013,11, 6477-6482

Permissions

Request permissions

N-Heterocyclic carbene catalyzed regioselective oxo-acyloxylation of alkenes with aromatic aldehydes: a high yield synthesis of α-acyloxy ketones and esters

R. N. Reddi, P. V. Malekar and A. Sudalai, Org. Biomol. Chem., 2013, 11, 6477 DOI: 10.1039/C3OB41551A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements