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Issue 37, 2013
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N-Heterocyclic carbene-catalyzed highly enantioselective synthesis of substituted dihydropyranopyrazolones

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Abstract

Highly optically pure multisubstituted dihydropyrano[2,3-c]pyrazol-6-(1H)-ones were synthesized via the N-heterocyclic carbene-catalyzed enantioselective [4 + 2] annulation of α-chloroaldehydes and pyrazolone-derived oxodienes.

Graphical abstract: N-Heterocyclic carbene-catalyzed highly enantioselective synthesis of substituted dihydropyranopyrazolones

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Publication details

The article was received on 15 Jul 2013, accepted on 31 Jul 2013 and first published on 01 Aug 2013


Article type: Communication
DOI: 10.1039/C3OB41455H
Citation: Org. Biomol. Chem., 2013,11, 6255-6257
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    N-Heterocyclic carbene-catalyzed highly enantioselective synthesis of substituted dihydropyranopyrazolones

    H. Zhang, H. Lv and S. Ye, Org. Biomol. Chem., 2013, 11, 6255
    DOI: 10.1039/C3OB41455H

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