Jump to main content
Jump to site search

Issue 34, 2013
Previous Article Next Article

One-pot synthesis of S-alkyl dithiocarbamates via the reaction of N-tosylhydrazones, carbon disulfide and amines

Author affiliations

Abstract

A new, convenient and efficient transition metal-free synthesis of S-alkyl dithiocarbamates through one-pot reaction of N-tosylhydrazones, carbon disulfide and amines is reported. Tosylhydrazones derived from various aromatic and aliphatic ketones or aldehydes were tested and gave dithiocarbamates in good to excellent yields. The tosylhydrazones can be generated in situ without isolation, which provides a simpler one-pot method to synthesize dithiocarbamates via the reaction of carbonyl compounds, carbon disulfide and amines in the presence of 4-methylbenzenesulfonohydrazide.

Graphical abstract: One-pot synthesis of S-alkyl dithiocarbamates via the reaction of N-tosylhydrazones, carbon disulfide and amines

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 14 Apr 2013, accepted on 23 Jun 2013 and first published on 25 Jun 2013


Article type: Paper
DOI: 10.1039/C3OB40745D
Citation: Org. Biomol. Chem., 2013,11, 5615-5620
  •   Request permissions

    One-pot synthesis of S-alkyl dithiocarbamates via the reaction of N-tosylhydrazones, carbon disulfide and amines

    Q. Sha and Y. Wei, Org. Biomol. Chem., 2013, 11, 5615
    DOI: 10.1039/C3OB40745D

Search articles by author