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Issue 10, 2013
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Synthesis and spectroscopic properties of fluorescent 5-benzimidazolyl-2′-deoxyuridines 5-fdU probes obtained from o-phenylenediamine derivatives

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Abstract

Fluorescent nucleosides (dUbmz) with desirable fluorescence quantum yield (Φ) are synthesized from almost non-fluorescent 5-fdU and o-phenylenediamine derivatives. The fluorescence of these nucleosides is quite sensitive to pH and organic solvents. 4-Methoxybenzene-1,2-diamine was used for the detection of 5-fdU among natural nucleosides.

Graphical abstract: Synthesis and spectroscopic properties of fluorescent 5-benzimidazolyl-2′-deoxyuridines 5-fdU probes obtained from o-phenylenediamine derivatives

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Publication details

The article was received on 31 Dec 2012, accepted on 22 Jan 2013 and first published on 22 Jan 2013


Article type: Communication
DOI: 10.1039/C3OB27519A
Citation: Org. Biomol. Chem., 2013,11, 1610-1613
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    Synthesis and spectroscopic properties of fluorescent 5-benzimidazolyl-2′-deoxyuridines 5-fdU probes obtained from o-phenylenediamine derivatives

    P. Guo, X. Xu, X. Qiu, Y. Zhou, S. Yan, C. Wang, C. Lu, W. Ma, X. Weng, X. Zhang and X. Zhou, Org. Biomol. Chem., 2013, 11, 1610
    DOI: 10.1039/C3OB27519A

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