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Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand
; Fax: +66 2 644 5126
; Tel: +66 2 201 5158
Org. Biomol. Chem., 2013,11, 2022-2033
08 Nov 2012,
07 Jan 2013
First published online
09 Jan 2013
PhSCF2SiMe3 (1) underwent fluoride-catalyzed nucleophilic addition to the carbonyl group of anhydrides to provide the corresponding γ-difluoro(phenylsulfanyl)methyl γ-lactols, which were employed for the synthesis of γ-difluoromethylated γ-lactams.
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Organic & Biomolecular Chemistry
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