State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China
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Org. Biomol. Chem., 2013,11, 1602-1605
11 Nov 2012,
14 Jan 2013
First published online
21 Jan 2013
Chiral phosphoric acid works together with Hoveyda–Grubbs II catalyst enabling highly efficient synthesis of enantioenriched tetrahydro-β-carboline (up to 95% yield, 90% ee) through an olefin isomerization/Pictet–Spengler cascade reaction via sequential catalysis.
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Organic & Biomolecular Chemistry
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