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Hypoxia-sensitive bis(2-(2′-benzothienyl)pyridinato-N,C3′)iridium[poly(n-butyl cyanoacrylate]/chitosan nanoparticles and their phosphorescence tumor imaging in vitro and in vivo

Yun Zeng,a   Shaojuan Zhang,b   Menghui Jia,c   Yang Liu,d   Jin Shang,b   Youmin Guo,b   Jianhua Xuc and   Daocheng Wu*a  
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Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P. R. China
E-mail: wudaocheng@mail.xjtu.edu.cn;
Fax: +86 2982663941 ;
Tel: +86 2982663941
Department of Radiology, First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710061, P. R. China
State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, P. R. China
School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P. R. China
Nanoscale, 2013,5, 12633-12644

DOI: 10.1039/C3NR04349E
Received 16 Aug 2013, Accepted 13 Oct 2013
First published online 14 Oct 2013
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