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Issue 24, 2013
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Quantum dot approaches for target-based drug screening and multiplexed active biosensing

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Abstract

Biomolecule detection using quantum dots (Qdots), nanometer-sized semiconductor crystals, effectively addresses the limitations associated with conventional optical and biochemical techniques, as Qdots offer several key advantages over traditional fluorophores. In this minireview, we discuss the role of Qdots as a central nanoscaffold for the polyvalent assembly of multifunctional biomolecular probes and describe recent advances in Qdot-based biorecognition. Specifically, we focus on Qdot applications in target-based, drug screening assays and real-time active biosensing of cellular processes.

Graphical abstract: Quantum dot approaches for target-based drug screening and multiplexed active biosensing

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Publication details

The article was received on 23 Apr 2013, accepted on 27 Jul 2013 and first published on 14 Aug 2013


Article type: Minireview
DOI: 10.1039/C3NR02019C
Citation: Nanoscale, 2013,5, 12072-12081
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    Quantum dot approaches for target-based drug screening and multiplexed active biosensing

    O. Kovtun, X. Arzeta-Ferrer and S. J. Rosenthal, Nanoscale, 2013, 5, 12072
    DOI: 10.1039/C3NR02019C

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