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Modifying mesoporous silica nanoparticles to avoid the metabolic deactivation of 6-mercaptopurine and methotrexate in combinatorial chemotherapy

Wenjing Wang,a   Chenjie Fang,*a   Xiaozhu Wang,a   Yuxi Chen,a   Yaonan Wang,d   Wei Feng,b   Chunhua Yan,b   Ming Zhao*ac and   Shiqi Peng*a  
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Corresponding authors
College of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China
E-mail: sqpeng@bjmu.edu.cn
Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Rare Earth Materials Chemistry and Applications & PKU-HKU Joint Laboratory on Rare Earth Materials and Bioinorganic Chemistry, Peking University, Beijing 100871, China
Faculty of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan
Medical Experiment and Test Center, Capital Medical University, Beijing 100069, China
Nanoscale, 2013,5, 6249-6253

DOI: 10.1039/C3NR00227F
Received 13 Jan 2013, Accepted 31 Mar 2013
First published online 03 Apr 2013
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