Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 10, 2013
Previous Article Next Article

Synthesis of [18F]fluoro-pivalic acid: an improved PET imaging probe for the fatty acid synthesis pathway in tumours

Author affiliations

Abstract

[18F]Fluoro-pivalic acid ([18F]FPIA), an analogue of [18F]fluoroacetate bearing a dimethyl moiety on C-2, has been radiosynthesised and evaluated in vivo. [18F]FPIA has high tumour uptake and, unlike [18F]fluoroacetate, does not defluorinate.

Graphical abstract: Synthesis of [18F]fluoro-pivalic acid: an improved PET imaging probe for the fatty acid synthesis pathway in tumours

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 13 Jun 2013, accepted on 16 Jul 2013 and first published on 18 Jul 2013


Article type: Concise Article
DOI: 10.1039/C3MD00169E
Citation: Med. Chem. Commun., 2013,4, 1350-1353
  •   Request permissions

    Synthesis of [18F]fluoro-pivalic acid: an improved PET imaging probe for the fatty acid synthesis pathway in tumours

    F. Pisaneschi, T. H. Witney, L. Iddon and E. O. Aboagye, Med. Chem. Commun., 2013, 4, 1350
    DOI: 10.1039/C3MD00169E

Search articles by author