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Issue 6, 2013
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Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

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Abstract

Rapid and specific rare cell detection for point-of-care testing requires an integration of the sample preparation for flow cytometry. To achieve such a challenging goal we have developed a magnetic flow cytometry technique which applies magnetophoresis to perform cell enrichment, focusing, and background elimination in a single step. Time-of-flight measurements are performed with integrated magnetic sensors to detect specifically cancer cells and cell diameters in whole blood.

Graphical abstract: Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

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Publication details

The article was received on 27 Nov 2012, accepted on 17 Jan 2013 and first published on 18 Jan 2013


Article type: Technical Innovation
DOI: 10.1039/C3LC41310A
Citation: Lab Chip, 2013,13, 1035-1038
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    Time-of-flight magnetic flow cytometry in whole blood with integrated sample preparation

    M. Helou, M. Reisbeck, S. F. Tedde, L. Richter, L. Bär, J. J. Bosch, R. H. Stauber, E. Quandt and O. Hayden, Lab Chip, 2013, 13, 1035
    DOI: 10.1039/C3LC41310A

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