Jump to main content
Jump to site search

Issue 5, 2013
Previous Article Next Article

Application of a micro-droplet generator for an ICP-sector field mass spectrometer – optimization and analytical characterization

Author affiliations

Abstract

A micro-droplet generator (μDG) sample introduction system was coupled to a sector field ICP-MS instrument to investigate the analytical figures of merit with respect to single cell analysis. The sector field instrument was operated for the first time in a fast scanning mode (E-scan) with the shortest time resolution of 100 μs to measure the single droplet time resolved and using the original detector in a pulse counting mode without modification of the existing electronics. For reduction of the droplet diameter a triple pulse mode of the droplet generator was applied and a droplet diameter down to 23 μm has been achieved for this investigation with a 100% transport efficiency of droplets. Signal duration times of single droplets of less than 500 μs have been measured. Overall detection efficiencies in the range of 10−3 counts per atom have been achieved and absolute limits of detection range between 120 ag for Fe and 1.1 ag for Mg as a mean value from 1000 droplet events.

Graphical abstract: Application of a micro-droplet generator for an ICP-sector field mass spectrometer – optimization and analytical characterization

Back to tab navigation

Publication details

The article was received on 17 Jul 2012, accepted on 06 Dec 2012 and first published on 04 Jan 2013


Article type: Paper
DOI: 10.1039/C2JA30207A
Citation: J. Anal. At. Spectrom., 2013,28, 646-656
  •   Request permissions

    Application of a micro-droplet generator for an ICP-sector field mass spectrometer – optimization and analytical characterization

    K. Shigeta, H. Traub, U. Panne, A. Okino, L. Rottmann and N. Jakubowski, J. Anal. At. Spectrom., 2013, 28, 646
    DOI: 10.1039/C2JA30207A

Search articles by author

Spotlight

Advertisements