Jump to main content
Jump to site search

Issue 1, 2013
Previous Article Next Article

Common pitfalls in nanotechnology: lessons learned from NCI's Nanotechnology Characterization Laboratory

Author affiliations

Abstract

The Nanotechnology Characterization Laboratory's (NCL) unique set-up has allowed our lab to handle and test a variety of nanoparticle platforms intended for the delivery of cancer therapeutics and/or imaging contrast agents. Over the last six years, the NCL has characterized more than 250 different nanomaterials from more than 75 different investigators. These submitted nanomaterials stem from a range of backgrounds and experiences, including government, academia and industry. This has given the NCL a unique and valuable opportunity to observe trends in nanoparticle safety and biocompatibility, as well as note some of the common mistakes and oversights of nanoformulation. While not exhaustive, this article aims to share some of the most common pitfalls observed by the NCL as they relate to nanoparticle synthesis, purification, characterization and analysis.

Graphical abstract: Common pitfalls in nanotechnology: lessons learned from NCI's Nanotechnology Characterization Laboratory

Back to tab navigation

Publication details

The article was received on 14 May 2012, accepted on 12 Jun 2012 and first published on 14 Jun 2012


Article type: Perspective
DOI: 10.1039/C2IB20117H
Citation: Integr. Biol., 2013,5, 66-73
  •   Request permissions

    Common pitfalls in nanotechnology: lessons learned from NCI's Nanotechnology Characterization Laboratory

    R. M. Crist, J. H. Grossman, A. K. Patri, S. T. Stern, M. A. Dobrovolskaia, P. P. Adiseshaiah, J. D. Clogston and S. E. McNeil, Integr. Biol., 2013, 5, 66
    DOI: 10.1039/C2IB20117H

Search articles by author

Spotlight

Advertisements