Issue 11, 2013
From the journal:

Green Chemistry

Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction†

Yu Wei,a   Jinghua Tang,a   Xuefeng Conga  and  Xiaoming Zeng*a  

* Corresponding authors

a Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China
E-mail: zengxiaoming@mail.xjtu.edu.cn
Fax: (+81)-29-83395321
Tel: (+81)-29-83395321

Abstract

Metal-free synthesis of chalcone derivatives through a tandem cross-dehydrogenative-coupling/elimination reaction is described. A simple and inexpensive ammonium persulfate salt enables the reaction between ketones and benzylamines to proceed with high stereoselectivity and good functional group compatibility.

Graphical abstract: Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction

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Article information

DOI
https://doi.org/10.1039/C3GC41403E
Article type
Communication
Submitted
16 Jul 2013
Accepted
25 Aug 2013
First published
27 Aug 2013

Green Chem., 2013,15, 3165-3169

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Practical metal-free synthesis of chalcone derivatives via a tandem cross-dehydrogenative-coupling/elimination reaction

Y. Wei, J. Tang, X. Cong and X. Zeng, Green Chem., 2013, 15, 3165 DOI: 10.1039/C3GC41403E

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