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Issue 3, 2013
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Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

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Abstract

A range of alternative solvents have been evaluated within amidation reactions employing common coupling reagents with a view to identifying suitable replacements for dichloromethane and N,N-dimethylformamide.

Graphical abstract: Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

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Publication details

The article was received on 27 Nov 2012, accepted on 19 Dec 2012 and first published on 19 Dec 2012


Article type: Communication
DOI: 10.1039/C2GC36900A
Citation: Green Chem., 2013,15, 596-600
  • Open access: Creative Commons BY license
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    Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

    D. S. MacMillan, J. Murray, H. F. Sneddon, C. Jamieson and A. J. B. Watson, Green Chem., 2013, 15, 596
    DOI: 10.1039/C2GC36900A

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