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Development of ruthenium(II) complexes as topical antibiotics against methicillin resistant Staphylococcus aureus

P.-L. Lam,a   G.-L. Lu,bc   K.-M. Hon,b   K.-W. Lee,b   C.-L. Ho,b   X. Wang,b   J. C.-O. Tang,a   K.-H. Lam,a   R. S.-M. Wong,d   S. H.-L. Kok,e   Z.-X. Bian,f   H. Li,*g   K. K.-H. Lee,*e   R. Gambari,*h   C.-H. Chui*f and   W.-Y. Wong*bi  
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a
State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, P.R. China
b
Institute of Molecular Functional Materials, Department of Chemistry and Institute of Advanced Materials, Hong Kong Baptist University, Hong Kong, P.R. China
E-mail: rwywong@hkbu.edu.hk;
Fax: +852-3411 7348 ;
Tel: +852-3411 7074
c
Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, New Zealand
d
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, P.R. China
e
School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, P.R. China
E-mail: kaholee@cuhk.edu.hk;
Fax: +852-2603 5139 ;
Tel: +852-3943 6785
f
Clinical Division, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, P.R. China
E-mail: chchui@hkbu.edu.hk;
Fax: +852-2637 5396 ;
Tel: +852-2632 1500
g
College of Life and Environmental Sciences, Minzu University of China, Beijing 100081, P.R. China
E-mail: lihuamuc@gmail.com
h
Centre of Biotechnology, Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy
E-mail: gam@unife.it;
Fax: +39-532-202723 ;
Tel: +39-532-974443
i
Institute of Polymer Optoelectronic Materials and Devices, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, P.R. China
Dalton Trans., 2014,43, 3949-3957

DOI: 10.1039/C3DT52879K
Received 13 Oct 2013, Accepted 14 Dec 2013
First published online 16 Dec 2013
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