Jump to main content
Jump to site search

Issue 45, 2013
Previous Article Next Article

Human serum albumin mutants complexed Mn(III) protoporphyrin IX as superoxide dismutase mimics

Author affiliations

Abstract

Genetically engineered human serum albumin (HSA) mutants complexed Mn(III) protoporphyrin IX (MnPP) in the haem pocket showed superoxide dismutase activity. Replacement of a proximal Tyr-161 by non-coordinating Leu caused a remarkable increase in enzyme activity.

Graphical abstract: Human serum albumin mutants complexed Mn(iii) protoporphyrin IX as superoxide dismutase mimics

Back to tab navigation

Supplementary files

Publication details

The article was received on 31 May 2013, accepted on 28 Jun 2013 and first published on 28 Jun 2013


Article type: Communication
DOI: 10.1039/C3DT51418H
Citation: Dalton Trans., 2013,42, 15889-15892
  •   Request permissions

    Human serum albumin mutants complexed Mn(III) protoporphyrin IX as superoxide dismutase mimics

    R. Kato, Y. Kobayashi, M. Akiyama and T. Komatsu, Dalton Trans., 2013, 42, 15889
    DOI: 10.1039/C3DT51418H

Search articles by author

Spotlight

Advertisements