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Issue 19, 2013
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Recent advances in the Willgerodt–Kindler reaction

Daniel L. Priebbenowa  and  Carsten Bolm*a 
Author affiliations

* Corresponding authors

a Institut für Organische Chemie, RWTH Aachen University, Landoltweg 1, D-52056 Aachen, Germany
E-mail: carsten.bolm@oc.rwth-aachen.de
Fax: +49 241 8092391
Tel: +49 241 8094675

Abstract

The Willgerodt–Kindler reaction has, in recent years, received limited attention and application in synthetic organic chemistry. With the advent of new technology such as microwave-assisted heating, several new, high-yielding, practical, and more environmentally friendly reaction protocols have been developed. This review aims to once again draw attention to this relatively underutilised process by highlighting the recent developments in the Willgerodt–Kindler reaction in the synthesis of (thio)amides, carboxylic acids, and heterocycles.

Graphical abstract: Recent advances in the Willgerodt–Kindler reaction

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Publication details

The article was received on 10 May 2013 and first published on 24 Jun 2013


Article type: Review Article
DOI: 10.1039/C3CS60154D
Citation: Chem. Soc. Rev., 2013,42, 7870-7880
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    Recent advances in the Willgerodt–Kindler reaction

    D. L. Priebbenow and C. Bolm, Chem. Soc. Rev., 2013, 42, 7870
    DOI: 10.1039/C3CS60154D

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