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Issue 14, 2013
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Recent progress in luminescent and colorimetric chemosensors for detection of thiols

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Abstract

In the past few decades, the development of optical probes for thiols has attracted great attention because of the biological importance of the thiol-containing molecules such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH). This tutorial review focuses on various thiol detection methods based on luminescent or colorimetric spectrophotometry published during the period 2010–2012. The discussion covers a diversity of sensing mechanisms such as Michael addition, cyclization with aldehydes, conjugate addition–cyclization, cleavage of sulfonamide and sulfonate esters, thiolhalogen nucleophilic substitution, disulfide exchange, native chemical ligation (NCL), metal complex-displace coordination, and nanomaterial-related and DNA-based chemosensors.

Graphical abstract: Recent progress in luminescent and colorimetric chemosensors for detection of thiols

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Publication details

The article was received on 25 Jan 2013 and first published on 20 May 2013


Article type: Tutorial Review
DOI: 10.1039/C3CS60024F
Citation: Chem. Soc. Rev., 2013,42, 6019-6031
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    Recent progress in luminescent and colorimetric chemosensors for detection of thiols

    H. S. Jung, X. Chen, J. S. Kim and J. Yoon, Chem. Soc. Rev., 2013, 42, 6019
    DOI: 10.1039/C3CS60024F

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