Issue 4, 2013

Anion binding in water at lanthanide centres: from structure and selectivity to signalling and sensing

Abstract

Reversible anion binding at lanthanide centres in aqueous media has emerged as an effective means of signalling and sensing the presence of selected anions. The constitution and configuration of a wide range of anion adducts has been defined by X-ray analyses and NMR methods, and both chelating and monodentate binding modes characterised. Variation of the lanthanide ion modulates charge density, and ligand modification allows alteration of both the peripheral electrostatic gradient and the local steric demand at the metal centre. Thus, selectivity for a target anion can be engineered, and the affinity constant modulated to target the desired concentration range. Changes in anion concentration can be monitored rapidly, accurately and with high spatial resolution using optical emission spectroscopy and microscopy, facilitating the measurement of anions such as bicarbonate, lactate, citrate and urate in a variety of bio-fluids.

Graphical abstract: Anion binding in water at lanthanide centres: from structure and selectivity to signalling and sensing

Article information

Article type
Tutorial Review
Submitted
16 Apr 2012
First published
03 Jul 2012

Chem. Soc. Rev., 2013,42, 1652-1666

Anion binding in water at lanthanide centres: from structure and selectivity to signalling and sensing

S. J. Butler and D. Parker, Chem. Soc. Rev., 2013, 42, 1652 DOI: 10.1039/C2CS35144G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements