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Issue 15, 2013
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Recent developments and future directions in SERS for bioanalysis

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Abstract

The ability to develop new and sensitive methods of biomolecule detection is crucial to the advancement of pre-clinical disease diagnosis and effective patient specific treatment. Surface enhanced Raman scattering (SERS) is an optical spectroscopy amenable to this goal, as it is capable of extremely sensitive biomolecule detection and multiplexed analysis. This perspective highlights where SERS has been successfully used to detect target biomolecules, specifically DNA and proteins, and where in vivo analysis has been successfully utilised. The future of SERS development is discussed and emphasis is placed on the steps required to transport this novel technique from the research laboratory to a clinical setting for medical diagnostics.

Graphical abstract: Recent developments and future directions in SERS for bioanalysis

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Publication details

The article was received on 31 Oct 2012, accepted on 11 Dec 2012 and first published on 15 Jan 2013


Article type: Perspective
DOI: 10.1039/C2CP43859C
Citation: Phys. Chem. Chem. Phys., 2013,15, 5312-5328
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    Recent developments and future directions in SERS for bioanalysis

    M. M. Harper, K. S. McKeating and K. Faulds, Phys. Chem. Chem. Phys., 2013, 15, 5312
    DOI: 10.1039/C2CP43859C

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