Issue 32, 2013

Polymorphic transformation of artemisinin by high temperature extrusion

Abstract

This communication reports a novel solvent free method to generate and stabilise the triclinic form of artemisinin. We show that the stability of the triclinic form obtained by high temperature extrusion is greater than that of material made using a solvent based technique.

Graphical abstract: Polymorphic transformation of artemisinin by high temperature extrusion

Supplementary files

Article information

Article type
Communication
Submitted
25 Apr 2013
Accepted
10 Jun 2013
First published
11 Jun 2013

CrystEngComm, 2013,15, 6297-6300

Polymorphic transformation of artemisinin by high temperature extrusion

C. Kulkarni, J. Kendrick, A. Kelly, T. Gough, R. C. Dash and A. Paradkar, CrystEngComm, 2013, 15, 6297 DOI: 10.1039/C3CE40726H

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