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Issue 21, 2013
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Facile in vitro hydroxyapatite remineralization of human enamel with remarkable hardness

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Abstract

The fabrication of enamel-mimicking material for clinical enamel remineralization remains a challenge. In this work, we proposed a facile and economical biomimetic strategy for achieving in vitro hydroxyapatite (HAP) remineralization on eroded human enamel using nacre water-soluble matrix (WSM) as template. X-ray diffraction (XRD) analysis and Fourier transformed infrared (FTIR) spectroscopy demonstrated that WSM facilitated the formation of HAP with a similar composition and structure to the natural enamel under mild conditions. Microscopic investigations revealed that the WSM-induced HAP nanorods were well bundled in parallel and densely arranged into highly-ordered units as compared to loose and disordered HAP crystals formed in the absence of WSM. The ideal features, smoothness and hardness of the WSM-induced HAP were further confirmed by the atomic force microscope (AFM) and digital Vicker's Hardness tester. We also discussed the role of WSM in inducing the highly-ordered HAP. The finding in this work provides new threads for the development of novel dental materials for clinical caries management.

Graphical abstract: Facile in vitro hydroxyapatite remineralization of human enamel with remarkable hardness

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Publication details

The article was received on 30 Nov 2012, accepted on 21 Mar 2013 and first published on 21 Mar 2013


Article type: Paper
DOI: 10.1039/C3CE26947G
Citation: CrystEngComm, 2013,15, 4351-4356
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    Facile in vitro hydroxyapatite remineralization of human enamel with remarkable hardness

    X. Li, D. Pan, S. Lin, Z. Zhuang and Z. Lin, CrystEngComm, 2013, 15, 4351
    DOI: 10.1039/C3CE26947G

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