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Issue 7, 2013
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Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

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Abstract

We demonstrate how solution crystallization of lamotrigine with flexible alkane dicarboxylic acids with different chain lengths (adipic acid and pimelic acid) generates a series of four isostructural solvated three-component salts. The analysis of their crystal structures shows that isostructurality is achieved by the combination of robust hydrogen bonding motifs and the incorporation of solvent guest molecules.

Graphical abstract: Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

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Publication details

The article was received on 31 Oct 2012, accepted on 29 Nov 2012 and first published on 29 Nov 2012


Article type: Paper
DOI: 10.1039/C2CE26791H
Citation: CrystEngComm, 2013,15, 1332-1338
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    Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion

    J. Galcera, T. Friščić, E. Molins and W. Jones, CrystEngComm, 2013, 15, 1332
    DOI: 10.1039/C2CE26791H

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