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Issue 91, 2013
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“Clickable” LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies

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Abstract

Herein we describe fluorescent oligonucleotides prepared by click chemistry between novel alkyne-modified locked nucleic acid (LNA) strands and a series of fluorescent azides for homogeneous (all-in-solution) detection of nucleic acids and autoimmune antibodies.

Graphical abstract: “Clickable” LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies

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Publication details

The article was received on 20 Jul 2013, accepted on 19 Sep 2013 and first published on 27 Sep 2013


Article type: Communication
DOI: 10.1039/C3CC45507F
Citation: Chem. Commun., 2013,49, 10751-10753
  • Open access: Creative Commons BY-NC license
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    “Clickable” LNA/DNA probes for fluorescence sensing of nucleic acids and autoimmune antibodies

    A. S. Jørgensen, P. Gupta, J. Wengel and I. K. Astakhova, Chem. Commun., 2013, 49, 10751
    DOI: 10.1039/C3CC45507F

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