Jump to main content
Jump to site search

Issue 74, 2013
Previous Article Next Article

An efficient synthetic route to carbocyclic enaminonitriles via Lewis acid catalysed domino-ring-opening-cyclisation (DROC) of donor–acceptor cyclopropanes with malononitrile

Author affiliations

Abstract

A highly efficient strategy for the synthesis of functionalised carbocyclic enaminonitriles in excellent yields has been described. The reaction utilises Yb(OTf)3 catalysed C–C bond cleavage and two simultaneous C–C bond formations of donor–acceptor (DA)-cyclopropanes with malononitrile anions in a domino fashion.

Graphical abstract: An efficient synthetic route to carbocyclic enaminonitriles via Lewis acid catalysed domino-ring-opening-cyclisation (DROC) of donor–acceptor cyclopropanes with malononitrile

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Jun 2013, accepted on 17 Jul 2013 and first published on 18 Jul 2013


Article type: Communication
DOI: 10.1039/C3CC44533J
Citation: Chem. Commun., 2013,49, 8205-8207
  •   Request permissions

    An efficient synthetic route to carbocyclic enaminonitriles via Lewis acid catalysed domino-ring-opening-cyclisation (DROC) of donor–acceptor cyclopropanes with malononitrile

    M. K. Ghorai, R. Talukdar and D. P. Tiwari, Chem. Commun., 2013, 49, 8205
    DOI: 10.1039/C3CC44533J

Search articles by author

Spotlight

Advertisements