The 1917 total synthesis of tropinone by Sir Robert Robinson represents a landmark achievement in organic synthesis. Decades ahead of its time in terms of its retrosynthetic logic and biomimetic approach, the elegant combination of these two elements in this synthesis continues to serve as an inspiration for the development of new and efficient strategies for complex molecule synthesis.
The article was received on 14 Jun 2013, accepted on 24 Sep 2013 and first published on 27 Sep 2013
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