Issue 66, 2013

Active ion transporters from readily accessible acyclic octapeptides containing 3-aminobenzoic acid and alanine

Abstract

Ion transporters have been developed from acyclic octapeptides comprising L/D alanine and m-aminobenzoic acid. These octapeptides transport cations up to 3 times faster than their cyclic analog through lipid vesicles. Preliminary CD, XRD and computational studies allude to a 6–9 Å wide tetrameric ion channel as the active ion transporter.

Graphical abstract: Active ion transporters from readily accessible acyclic octapeptides containing 3-aminobenzoic acid and alanine

Supplementary files

Article information

Article type
Communication
Submitted
05 Jun 2013
Accepted
24 Jun 2013
First published
24 Jun 2013

Chem. Commun., 2013,49, 7340-7342

Active ion transporters from readily accessible acyclic octapeptides containing 3-aminobenzoic acid and alanine

B. P. Benke and N. Madhavan, Chem. Commun., 2013, 49, 7340 DOI: 10.1039/C3CC44224A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements