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Issue 58, 2013
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Thermoresponsive cyclic peptide – poly(2-ethyl-2-oxazoline) conjugate nanotubes

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Abstract

We describe the synthesis of self-assembling cyclic octapeptides of alternating D- and L-chirality conjugated to two poly(2-ethyl-2-oxazoline) chains. The resulting conjugates form nanotubes in water, which are reversibly transformed into microparticles as the temperature reaches the cloud point temperature of the conjugate.

Graphical abstract: Thermoresponsive cyclic peptide – poly(2-ethyl-2-oxazoline) conjugate nanotubes

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Publication details

The article was received on 30 Mar 2013, accepted on 04 Jun 2013 and first published on 04 Jun 2013


Article type: Communication
DOI: 10.1039/C3CC42327A
Citation: Chem. Commun., 2013,49, 6522-6524
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    Thermoresponsive cyclic peptide – poly(2-ethyl-2-oxazoline) conjugate nanotubes

    R. Chapman, P. J. M. Bouten, R. Hoogenboom, K. A. Jolliffe and S. Perrier, Chem. Commun., 2013, 49, 6522
    DOI: 10.1039/C3CC42327A

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