Issue 55, 2013
From the journal:

Chemical Communications

Aptamer degradation inhibition combined with DNAzyme cascade-based signal amplification for colorimetric detection of proteins†

Jishan Li,*a   Yuhua Jia,a   Jing Zheng,a   Wenwan Zhong,b   Guoli Shen,a   Ronghua Yang*a  and  Weihong Tana  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China
E-mail: jishanli@hnu.cn, Yangrh@pku.edu.cn
Fax: +86 731-88822523
Tel: +86 731-88822523

b Department of Chemistry, University of California-Riverside, California 92521, USA

Abstract

Combining the inhibition of aptamer degradation with DNA Enzyme (DNAzyme) cascade-based signal amplification, a label-free and sensitive colorimetric protein assay strategy was proposed.

Graphical abstract: Aptamer degradation inhibition combined with DNAzyme cascade-based signal amplification for colorimetric detection of proteins

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Article information

DOI
https://doi.org/10.1039/C3CC42148A
Article type
Communication
Submitted
27 Mar 2013
Accepted
16 May 2013
First published
16 May 2013

Chem. Commun., 2013,49, 6137-6139

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Aptamer degradation inhibition combined with DNAzyme cascade-based signal amplification for colorimetric detection of proteins

J. Li, Y. Jia, J. Zheng, W. Zhong, G. Shen, R. Yang and W. Tan, Chem. Commun., 2013, 49, 6137 DOI: 10.1039/C3CC42148A

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