Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 28, 2013
Previous Article Next Article

Polymerization of a peptide-based enzyme substrate

Author affiliations


Polymers of norbornenyl-modified peptide-based enzyme substrates have been prepared via ring-opening metathesis polymerization (ROMP). Peptides displayed on water-soluble homopolymers retain the ability to be enzymatically processed by a disease-associated enzyme. In contrast, when the peptides are densely arrayed on a nanoparticle derived from a self-assembled amphiphilic block-copolymer, they function with reduced activity as enzymatic substrates.

Graphical abstract: Polymerization of a peptide-based enzyme substrate

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 19 Jan 2013, accepted on 18 Feb 2013 and first published on 01 Mar 2013

Article type: Communication
DOI: 10.1039/C3CC40472B
Citation: Chem. Commun., 2013,49, 2873-2875
  •   Request permissions

    Polymerization of a peptide-based enzyme substrate

    M. E. Hahn, L. M. Randolph, L. Adamiak, M. P. Thompson and N. C. Gianneschi, Chem. Commun., 2013, 49, 2873
    DOI: 10.1039/C3CC40472B

Search articles by author