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Issue 38, 2013
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Efficient synthesis of [18F]trifluoromethane and its application in the synthesis of PET tracers

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Abstract

A new strategy towards [18F]trifluoromethyl-containing compounds is developed. [18F]trifluoromethane is synthesised in a fast and efficient manner and subsequently used in the reaction with aldehydes and ketones forming [18F]trifluoromethyl carbinols in good yields.

Graphical abstract: Efficient synthesis of [18F]trifluoromethane and its application in the synthesis of PET tracers

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Publication details

The article was received on 29 Oct 2012, accepted on 25 Mar 2013 and first published on 26 Mar 2013


Article type: Communication
DOI: 10.1039/C3CC37833K
Citation: Chem. Commun., 2013,49, 4018-4020
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    Efficient synthesis of [18F]trifluoromethane and its application in the synthesis of PET tracers

    D. van der Born, J. (. D. M. Herscheid, R. V. A. Orru and D. J. Vugts, Chem. Commun., 2013, 49, 4018
    DOI: 10.1039/C3CC37833K

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