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Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions

Lin Qiu,a   Xin Guo,a   Chaoqun Ma,a   Huang Qiu,a   Shunying Liu,*a   Liping Yanga and   Wenhao Hu*a  
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a
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, East China Normal University, 3663 North Zhongshan Rd., Shanghai, China
E-mail: syliu@sist.ecnu.edu.cn, whu@chem.ecnu.edu.cn;
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Chem. Commun., 2014,50, 2196-2198

DOI: 10.1039/C3CC49063G
Received 27 Nov 2013, Accepted 20 Dec 2013
First published online 23 Dec 2013
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